Extraction With Site Preservation Using Freeze-Dried Bone Allograft With a Human Amnion-Chorion Membrane vs Freeze-Dried Bone Allograft With a BI-Layer Porcine Derived Collagen Membrane: A Randomized Clinical Trial
Abstract
Introduction: Alveolar ridge preservation, also known as site preservation, using various techniques and materials, has been shown to decrease three-dimensional bone loss following tooth extraction. This randomized, single blinded study compared clinical outcomes of extraction with site preservation using freeze-dried bone allograft (FDBA) with either a porcine collagen (Bio-Gide) or human amnion-chorion (BioXclude) resorbable membrane. Methods: Patients treatment planned for tooth extraction and subsequent implant with intact adjacent teeth were enrolled. At time of extraction the site was preserved with FDBA and randomly allocated to receive either a Bio-Gide or BioXclude membrane.Probing depths and clinical attachment level were assessed on teeth adjacent to the extraction site at the time of extraction and at 18-20 weeks post-extraction. Vertical alveolar ridge change was measured using a customized stent at baseline and 18-20 weeks post-extraction. Horizontal alveolar ridge change was measured using stone models from alginate impressions that were taken at baseline, 12 weeks, and 18-20 weeks post-extraction. The rate of soft tissue closure post-extraction was recorded using intraoral measurements at baseline and at 1, 2, 4 and 6 weeks (or until closed). Results: Thirty-six patients and 40 teeth completed the study. The Bio-Gide group consisted of 19 teeth and the BioXclude group consisted of 21 teeth. From baseline to 18-20 weeks no significant differences were detected between the groups for any of the measured parameters. Both membranes had horizontal ridge width loss of 2.0mm and both membranes had an average vertical height loss of <1.0mm. For adjacent teeth, probing depth reduction was just under 1.0mm for each group and clinical attachment level loss was <1.0mm for both groups, with no significant difference between groups. Soft tissue closure was completed on average at 4 weeks for both groups.
Document Details
- Document Type
- Technical Report
- Publication Date
- Jun 01, 2019
- Accession Number
- AD1128082
Entities
People
- Elizabeth A. Polak
Organizations
- Uniformed Services University of the Health Sciences