Enhancing Immune Checkpoint Inhibitor Therapy in Kidney Cancer

Abstract

The purpose of this work is to develop strategies to enhance immune checkpoint inhibition in kidney cancer. The work is designed to test different strategies to induce or enhance the abscopal in a kidney cancer model by combining ablative techniques or TLR agonists withPD1 inhibitors. Animal Protocol is now ACURO and UTSW approved. Work will start as soon as no cost extension has been approved.

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Document Details

Document Type
Technical Report
Publication Date
Jan 01, 2021
Accession Number
AD1132037

Entities

People

  • Hans-joerg Hammers

Organizations

  • University of Texas Southwestern Medical Center

Tags

DTIC Thesaurus Topics

  • Abstracts
  • Antibodies
  • Availability
  • Biomedical Research
  • Cells
  • Classification
  • Combination Therapy
  • Contracts
  • Department Of Defense
  • Dermatologic Agents
  • Drug Therapy
  • Electronic Mail
  • Immunotherapy
  • Information Operations
  • Inhibition
  • Inhibitors
  • Kidney Cancer
  • Lymphocytes
  • Maryland
  • Radiation
  • Therapy

Readers

  • Clinical Trial Research.
  • Oncology