Systems of Thiamine Pyrophosphate Biosynthesis and Transport in Neisseria Gonorrhoeae
Abstract
Gonorrhea is the second-most commonly reported notifiable infection in the United States and a serious threat to public health. The rapid evolution of antibiotic resistance in Neisseria gonorrhoeae (Gc) has decreased the number of options available for treatment, and there has not been a successful vaccine developed for Gc due to the ability of the pathogen to evade detection and killing by the host immune system. Gc is an extremely successful human-specific pathogen that has tailored its genome to allow it to adapt to and survive in nutrient-restrictive environments.
Document Details
- Document Type
- Technical Report
- Publication Date
- Mar 20, 2018
- Accession Number
- AD1132839
Entities
People
- Riley T. Sennett
Organizations
- Uniformed Services University of the Health Sciences