A New, Simple, Rapid, On-Site Test for Detection of and Prevention from SARS-CoV Viruses

Abstract

Mesa Photonics developed a simple and fast test for detecting SARS coronavirus in infected cells. The test system consists of substrates that release fluorescent signals when they are cleaved by a SARS and a control protease. The Huorescent signals are detected simultaneously in one sample in a battery-operated handheld fluorometer. The SARS reporter substrate is not cleaved by human proteases or proteases from other coronaviruses. We demonstrate that 15,000 viruses can be detected in less than 6,000 cells in 15 minutes using crude, unpurified lysate.

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Document Details

Document Type
Technical Report
Publication Date
May 21, 2021
Accession Number
AD1134058

Entities

People

  • Daniel J. Kane
  • Frauke H. Rininsland

Tags

Communities of Interest

  • Biomedical

DTIC Thesaurus Topics

  • Amino Acids
  • Antigens
  • Cells
  • Chemistry
  • Coronaviruses
  • Covid-19
  • Detection
  • Disease Outbreaks
  • Health Services
  • Hygiene
  • Interferon
  • Medical Personnel
  • Mers-Cov
  • New Mexico
  • Proteins
  • Pulmonology
  • Sars
  • Therapy
  • Virus Diseases
  • Viruses
  • Zoonoses

Fields of Study

  • Biology

Readers

  • Analytical Chemistry
  • Infectious Disease/Epidemiology
  • Molecular and Cellular Biochemistry