Developing and Field-Testing Genetic Catabolic Probes for Monitored Natural Attenuation of 1,4-Dioxane

Abstract

Remediation of aquifers contaminated with 1,4-dioxane (dioxane) is a difficult task due to its extremely hydrophilic nature. Monitored natural attenuation (MNA), which relies primarily on biodegradation, is often the most cost-effective approach to manage large and dilute groundwater plumes of primary pollutants, such as those formed by dioxane. However, improved forensic tools are needed to ensure biodegradation is occurring at impacted sites. During this one-year project, catabolic biomarkers of high selectivity and sensitivity were developed to target (until now elusive) dioxane/tetrahydrofuran soluble di-iron monooxygenasegenes using Taqman chemistry. Further, dioxane degradation activity observed in microcosms prepared with groundwater samples and aquifer materials from multiple sites was found to be significantly correlated with the abundance of thmA/dxmA genes, suggesting the usefulness of this probe to assess feasibility of MNA/bioremediation and estimate degradation rates.

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Document Details

Document Type
Technical Report
Publication Date
Sep 30, 2019
Accession Number
AD1134898

Entities

People

  • Jacques Mathieu
  • Marcio B. Da Silva
  • Mengyan Li
  • Pedro J. Alvarez
  • Ya He
  • Yang Yu

Organizations

  • Rice University

Tags

DTIC Thesaurus Topics

  • Alkenes
  • Anti-Bacterial Agents
  • Bacterial Infections
  • Bacteriology
  • Biodegradation
  • Chemical Synthesis
  • Chemistry
  • Databases
  • Ecology
  • Ecotoxicology
  • Environmental Pollutants
  • Environmental Restoration And Remediation
  • Genetics
  • Information Science
  • Microbial Genetics
  • Microbiology
  • Microbiomes
  • Organic Chemistry
  • Pseudomonas Infections
  • Synthetic Biology

Fields of Study

  • Environmental science

Readers

  • Groundwater Contamination Remediation.
  • Oncology and Biomarker-Based Cancer Detection.

Technology Areas

  • Biotechnology
  • Biotechnology - Bioremediation