Protein Variational Autoencoders for Antibody Based Drug Design

Abstract

This report details the Year 1 efforts of the Naval Research Laboratory (NRL) toward the development of Artificial Intelligence/ Machine Learning (AI/ML) algorithms to enable directed modification of antibody and antibody-like proteins to enhance their pharmokinetic properties.

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Document Details

Document Type
Technical Report
Publication Date
Mar 15, 2021
Accession Number
AD1135092

Entities

People

  • George P. Anderson
  • Jerome E. Alvarez
  • Scott A. Walper
  • Scott N Dean

Organizations

  • United States Naval Research Laboratory

Tags

Communities of Interest

  • Autonomy

DTIC Thesaurus Topics

  • Algorithms
  • Amino Acids
  • Artificial Intelligence
  • Artificial Intelligence Software
  • Biomolecules
  • Computational Science
  • Data Mining
  • Deep Learning
  • Information Science
  • Machine Learning
  • Neural Networks
  • Proteins
  • Recurrent Neural Networks
  • Surface Plasmon Resonance
  • Surface Plasmons
  • Systems Biology
  • Test Methods

Readers

  • Molecular Genetics
  • Neural Network Machine Learning.
  • Research Science/Academic Research

Technology Areas

  • AI & ML
  • AI & ML - DoD AI Strategy