Using Emotional Expression as a Novel Indicator of Functional Outcomes and Facial Rehabilitation Following Face Transplantation via Software-Based Video AnalysisAnalysis

Abstract

Face transplantation (FT) outcomes have traditionally been defined by improvement of motor and sensory function. However, FT recipients seek to reintegrate into society, where ability to express emotions is integral to success. The ability to generate identifiable emotional expressions has not been yet successfully used as a quantitative outcome assessment in FT. Human observers use information from different areas of the face to successfully recognize expressed emotion. To the best of our knowledge, there is currently no established method to objectively assess expressed emotion the way human observers do in FT. Additionally, detection of immune rejection still poses challenges in the early stages after FT, and especially for visually impaired patients. There exists an unmet need for non-invasive, high-precision assessment of visual changes related to immune rejection of facial allografts. Aim 1: Quantitatively assess the ability to form identifiable facial emotional expression as a functional outcome of face transplantation. Aim 2: Develop software further for clinical monitoring of facial allograft rejection. Retrospective, matched-cohort study using 6 VCA recipients and 6 healthy subjects. Noldus video-analysis software will be used to detect emotional expression of all subjects.

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Document Details

Document Type
Technical Report
Publication Date
Jan 01, 2021
Accession Number
AD1135525

Entities

People

  • Bohdan Pomahač

Tags

DTIC Thesaurus Topics

  • Abstracts
  • Allografts
  • Biomedical Research
  • Data Processing
  • Detection
  • Detectors
  • Electromyography
  • Expressed Emotion
  • Facial Recognition
  • Happiness
  • Health Services
  • Hospitals
  • Indicators
  • Medical Personnel
  • Monitoring
  • Neural Networks
  • Observers
  • Pain
  • Quality Of Life
  • Recognition
  • Rehabilitation
  • Rejection
  • Test And Evaluation
  • Therapy
  • Transplantation
  • Transplants

Readers

  • Neuroscience
  • Psychological Intervention/Treatment for Stress, Anxiety, PTSD, and Related Emotional and Cognitive Health Symptoms.

Technology Areas

  • Biotechnology