Anesthesia Neurotoxicity in Congenital Heart Disease

Abstract

The proposed studies will provide cellular/molecular insights into caspase-induced nonapoptotic neuronal degeneration and will establish a highly translational treatment aimed at reducing neurotoxicity due to neonatal cardiac surgery and improving neurological outcome in children with CHD. The proposed study is of broad relevance for not only for CHD but other populations who need to undergo major surgery early in life.

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Document Details

Document Type
Technical Report
Publication Date
May 01, 2021
Accession Number
AD1138279

Entities

People

  • Nobuyuki Ishibashi

Organizations

  • Children's National Hospital

Tags

DTIC Thesaurus Topics

  • Brain
  • Cardiovascular Surgery
  • Cell Physiological Processes
  • Cells
  • Cellular Structures
  • Drug Abuse
  • Health Services
  • Intellectual Disability
  • Medical Personnel
  • Neurons
  • Stem Cells
  • Stress (Physiology)

Readers

  • Molecular and Cellular Biology
  • Neurotrauma and Rehabilitation Medicine.