Broad-Spectrum Inhibitors of Future Emerging Viruses

Abstract

The goal of our project is to implement a strategy for proactive acquisition of broad-spectrum antivirals against emerging viral pathogens prior to their entry into human populations during outbreaks. If successful, our longer-term goal is to develop broad-spectrum antiviral drugs that can be made available to military and medical personnel at risk of infection during deployment to affected geographical locales. The project addresses three of the FY18 PRMRP Topic Areas. "Emerging infectious diseases" is addressed directly, "vaccine development for infectious diseases" is addressed in spirit though our technology is not a vaccine and, as this project starts by consideration of the flavivirus family, "Guillain-Barre' Syndrome" is relevant since neurotropic species of the virus family are causally associated with GBS.

Open PDF

Document Details

Document Type
Technical Report
Publication Date
Mar 01, 2021
Accession Number
AD1139911

Entities

People

  • Antonito T Panganiban

Tags

DTIC Thesaurus Topics

  • Arboviruses
  • Artificial Intelligence
  • Biomedical Research
  • Covid-19
  • Disease Outbreaks
  • Infectious Diseases
  • Inhibitors
  • Medical Personnel
  • Molecules
  • Pandemics
  • Procurement
  • Proteins
  • Rna Viruses
  • Sars
  • Small Molecules
  • Virus Diseases
  • Viruses

Fields of Study

  • Medicine

Readers

  • Infectious Disease/Epidemiology
  • Systems Analysis and Design
  • Virology (or Medical Virology).

Technology Areas

  • Biotechnology