Refining the Procedures for Medial-Olivocochlear Reflex (MOCR) Assays: Decreasing the Contralateral Noise Reset Time Below 10 Seconds Can Affect Subsequent Transient-Evoked Otoacoustic Emission (TEOAE) Measurements
Abstract
The medial-olivocochlear reflex (MOCR) may indicate risk for noise-induced hearing loss, but human clinical trials are needed. The transient-evoked otoacoustic emission (TEOAE)-based assay we have developed for assessing the MOCR needs to be faster for clinical use. This assay uses a series of TEOAE tests with and without a contralateral elicitor, and the MOCR strength is derived from their difference. This experiment evaluated if the elicitor reset time, which allows time for the MOCR to recover before the next TEOAE test, could be reduced from 10 seconds without affecting the test results. Four reset times (1.5, 3, 5, and 10 seconds) were compared for three transient-evoked otoacoustic emission (TEOAE) stimulus levels: 47, 50, and 53 dB SPL. All three shorter reset times showed residual effects on the following TEOAE response in some ears. It was unclear to what extent this affected the derived MOCR as no consistent pattern was found. We recommend that the 10 second reset time is retained for now.
Document Details
- Document Type
- Technical Report
- Publication Date
- Jun 11, 2021
- Accession Number
- AD1144234
Entities
People
- Charlotte M. Reed
- Judi A. Lapsley Miller
- Lynne Marshall
- Timothy Villabona
- Zachary Perez
Organizations
- Massachusetts Institute of Technology
- Naval Submarine Medical Research Laboratory
- University of Connecticut