Evaluation of Hypotensive Resuscitation +/- Aeromedical Evacuation and the Effects of Oxygen Therapeutics During Prolonged Field Care in a Swine Polytrauma Model
Abstract
The objective of this study is to confirm our hypotheses related to the possible adverse effects of Prolonged Field Care (PFC) and aeromedical evacuation (AE) on polytrauma patients, and to evaluate if the use of an Oxygen Therapeutic (OT) during PFC can improve oxygenation and outcomes. We will test this hypothesis in a swine polytrauma model. Data from this study could potentially aid in the improvement of safety recommendations for prolonged field care, en route care, and aeromedical evacuation of combat casualties. Specific aims: This study aims at addressing the following research questions: 1) How does prolonged hypotensive resuscitation over 72 hours affect physiology and neurophysiology in polytrauma casualties? 2) What are the effects of transport/aeromedical evacuation after prolonged hypotensive resuscitation on physiology and neurophysiology in polytrauma casualties? 3) Does an OT improve systemic and cerebral oxygen delivery under conditions of prolonged hypotension in polytrauma patients?
Document Details
- Document Type
- Technical Report
- Publication Date
- Aug 31, 2021
- Accession Number
- AD1146857
Entities
People
- Carolyn Gosztyla
Organizations
- Naval Medical Research Center