Direct Current Stimulation for Pain Treatment of Gulf War Illness

Abstract

The purpose of this research is to study the pain modulation pathways that are thought to be the active in Gulf War Illness veterans with pain symptoms. By studying these pathways, the study aims to find a pain treatment that can improve the pain symptoms of patients diagnosed with GWI and to better understand the mechanism of action of the pain indicators. We intend to achieve this by applying non-invasive transcranial direct current stimulation (tDCS) to patients that will be randomly assigned to active/sham groups and by using behavioral and electrophysiological measures to assess the outcome of the experiments. These measures include a test battery to depict level of pain, electroencephalogram (EEG) and resting state functional magnetic resonance (rsfMRI). We plan to consent and enroll 60 patients that will undergo the entire procedure, which consists of pre-assessments, neurostimulation, post-assessments, and follow up visits at 4 weeks, 12 weeks and 24 weeks.

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Document Details

Document Type
Technical Report
Publication Date
Nov 01, 2020
Accession Number
AD1151171

Entities

People

  • Sven Vanneste

Organizations

  • University of Texas at Dallas

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DTIC Thesaurus Topics

  • Abstracts
  • Biomedical Research
  • Data Analysis
  • Data Processing
  • Direct Current
  • Diseases And Disorders
  • Electroencephalography
  • Electronic Mail
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  • Local Governments
  • Magnetic Resonance
  • Maryland
  • Medical Personnel
  • Navigational Equipment
  • Patent Applications
  • Patents
  • Persian Gulf Syndrome
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Readers

  • Brain and Cognitive Science; Experimental Psychology; Cognitive Neuroscience
  • Gulf War Illness and Chronic Multisymptom Illness in Veterans.
  • Mental Health of Military Veterans with Posttraumatic Stress Disorder (PTSD): Risk Factors, Prevalence, Symptoms, and Treatment.