Genomics of Early Lung Cancer Among Military Personnel (GELCAMP)

Abstract

Lung cancer is a leading cause of death worldwide, and improvements in morbidity and mortality hinge on continued investigation into the biology of cancer. Whole genome sequencing can uncover cancer-associated mutations that can meaningfully impact clinical care and decision-making. In this study, blood, bronchial epithelial cells and tumor tissue (as applicable) will be sequenced from 50 cases with confirmed cancer and 50 non-cancer controls. The resulting profiles will be analyzed for genetic markers that that may enable earlier diagnosis, guide therapy decisions and improve patient outcomes.

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Document Details

Document Type
Technical Report
Publication Date
Apr 01, 2021
Accession Number
AD1151179

Entities

People

  • Robert Browning

Organizations

  • Uniformed Services University of the Health Sciences
  • Walter Reed National Military Medical Center

Tags

DTIC Thesaurus Topics

  • Abstracts
  • Biological Markers
  • Biology
  • Biomedical Research
  • Cancer
  • Contracts
  • Covid-19
  • Department Of Defense
  • Extraction
  • Genetic Markers
  • Genomics
  • Lung Cancer
  • Maryland
  • Materials
  • Medical Personnel
  • Military Medicine
  • Military Personnel
  • Mutations
  • Neoplasms
  • Pilot Studies
  • Professional Development
  • Technology Transfer
  • Universities

Fields of Study

  • Biology

Readers

  • Molecular and genetic basis of cancer.
  • Oncology and Biomarker-Based Cancer Detection.
  • Systems Analysis and Design

Technology Areas

  • Biotechnology