Light-Activated Sealing to Improve Outcomes Following Penetrating Bowel Trauma

Abstract

The overarching hypothesis of this proposal is that a rapid, simple, light-activated sealing technology can provide a more secure wound closure and reduce complications leading to improved outcomes for wounded warfighters following traumatic penetrating colon injury. Penetrating bowel wounds can be rapidly sealed and stabilized using biocompatible patches in conjunction with light-activated bonding. Our objective is to determine the optimal implementation strategy for this technology in a large animal model that recapitulates the military trauma scenario and to address a priority research area in the Combat Casualty Care Research Program to identify and develop medical techniques and materiel for early intervention in life-threatening battle injuries.

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Document Details

Document Type
Technical Report
Publication Date
Aug 01, 2021
Accession Number
AD1152327

Entities

People

  • John A. Parrish
  • Robert W Redmond

Organizations

  • Massachusetts General Hospital

Tags

DTIC Thesaurus Topics

  • Abdomen
  • Abstracts
  • Battles
  • Biomedical Research
  • Blood
  • Casualties
  • Combat Casualty Care
  • Data Analysis
  • Health Services
  • Hemorrhagic Shock
  • Hospitals
  • Materials
  • Medical Personnel
  • Membranes
  • Military Medicine
  • Physicians
  • Postoperative Complications
  • Pressure Measurement
  • Standards
  • Surgery
  • Warfare
  • Wounds And Injuries

Fields of Study

  • Medicine

Readers

  • Defense Technology Research and Development.
  • Trauma Surgery or Emergency Medicine.