Boston Biorepository, Recruitment, and Integrative Network (BBRAIN) for GWI
Abstract
The primary objective of BBRAIN is to establish a retrospective and prospective biorepository network for GWI research by data mining from existing BBRAIN collaborator specimens and for recruiting 500 additional repository samples. The four prospective recruitment resource sites include Boston, Miami, Bronx and San Francisco. The BBRAIN structure provides centralized cataloguing and coordination of retrospective biorepository samples from 10 collaborating institutions who are sharing existing blood plasma, sera, PBMCs, cerebrospinal fluid, human-induced pluripotent stem cells (hiPSCs), DNA and saliva samples. Corresponding cognitive outcomes, brain imaging, demographics and health symptom surveys are included in the BBRAIN network datasets to allow for the comparison of biomarkers with behavioral outcomes. To date, data usage and material transfer agreements have been put in place with all sites and sharing has begun with retrospective data and outcomes. We have recruited 75 new study participants to date and have published six collaborative publications.
Document Details
- Document Type
- Technical Report
- Publication Date
- Sep 01, 2021
- Accession Number
- AD1153324
Entities
People
- Julia Golier
- Kimberly Sullivan
- Linda L Chao
- Nancy G. Klimas
Organizations
- Boston University Medical Campus