A Prospective, Randomized Investigation of "Plasma First Resuscitation" for Traumatic Hemorrhage and Attenuation of the Acute Coagulopathy of Trauma - PUPTH-IIA

Abstract

The COMBAT (Control of Major Bleeding After Trauma) study is a randomized clinical trial evaluating the early administration of plasma, compared to the standard crystalloid. Over the past year, we have worked on refining our procedures and workflows, collecting accurate and timely data, ensuring regulatory compliance, and communicating with all study team personnel at Denver Health and the University of Colorado Anschutz Medical Campus. We have enrolled a total of 98 patients to-date and 41 patients this reporting year. We have collected over 4,500 samples this year, in addition to submitting our annual continuing review, publishing and presenting several papers.

Open PDF

Document Details

Document Type
Technical Report
Publication Date
May 01, 2021
Accession Number
AD1153616

Entities

People

  • Arsen Ghasabyan
  • Ernest Moore
  • Jacob Feiler

Organizations

  • University of Colorado Denver

Tags

Communities of Interest

  • Biomedical

DTIC Thesaurus Topics

  • Arteries
  • Blood Coagulation Factors
  • Cardiovascular Physiological Phenomena
  • Chemical Synthesis
  • Chemistry
  • Health Services
  • Medical Personnel

Fields of Study

  • Medicine

Readers

  • Clinical Trial Research.
  • Trauma Surgery or Emergency Medicine.