Targeting Food Cue Reactivity and Satiety Sensitivity to Decrease Binge Eating and Weight
Abstract
The purpose of the study is to compare a novel treatment, named Regulation of Cues (ROC), to Cognitive Behavior Therapy (CBT), to address binge eating and weight loss in veterans. The objectives of the study are: 1) to evaluate feasibility and acceptability of ROC and CBT and 2) to evaluate the efficacy of both treatments on reduction of binge eating and weight among 120 Veterans with subclinical or clinical Binge Eating Disorder (BED) with comorbid overweight/obesity (OW/OB). By the end of Year 3, 102 participants were randomized into treatment (22 participants in Cohort 1, 31 participants in Cohort 2, 29 participants in Cohort 3, and 20 participants in Cohort 4; 85 percent of the study goal). We started recruitment of Cohort 5 by the end of Year 3. Assessments were conducted per schedule for each cohort. Cohort 3 participants completed treatment and Cohort 4 participants completed 12 of 18 scheduled treatment sessions by the end of Year 3. No unanticipated problems involving risk to subjects or others have occurred since the study began. Regulatory documents, amendments to research protocols, adverse events, and protocol deviations were submitted in a timely manner and approved/acknowledged by local IRBs and DoD HRPO. Data entry and cleaning are ongoing. The study continues to adapt to the restrictions caused by the COVID-19 pandemic by amending research protocols and minimized the impact on data collection and treatment.
Document Details
- Document Type
- Technical Report
- Publication Date
- Oct 01, 2021
- Accession Number
- AD1154963
Entities
People
- David Strong
- Kerri Boutelle
- Niloofar Afari
Organizations
- University of California, San Diego