Effects of Fluctuations in Oxygen Partial Pressure from Normoxia to Moderate Hyperoxia

Abstract

Pilots in modern tactical aircraft breathe oxygen-enriched gas supplied by onboard oxygen generating systems (OBOGS). These may provide their maximum possible oxygen fraction at all times (nominally 94%), or, like that in the F-35, control the oxygen fraction at lower concentrations on a schedule based on altitude. The altitude-based schedules have a wide band of acceptable oxygen concentrations, and OBOGS that follow them may supply gas concentrations that fluctuate within the acceptable band. This IRB-approved study addressed a concern that unsteady oxygen partial pressure might be related to physiological episodes (PEs). Oxygen concentrations of 21% (air) and 35% were supplied on the ground to approximate operational conditions in which the inhaled partial pressures fluctuate by 15% from normoxia to slight hyperoxia at a cabin altitude of 8,000 feet.

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Document Details

Document Type
Technical Report
Publication Date
Sep 01, 2021
Accession Number
AD1155417

Entities

People

  • Barbara E. Shykoff
  • Kara J Blacker
  • Lesley R. Lee

Organizations

  • Naval Medical Research Unit Dayton
  • Oak Ridge Institute for Science and Education

Tags

Communities of Interest

  • Biomedical

DTIC Thesaurus Topics

  • Accuracy
  • Air Breathing
  • Arteries
  • Blood
  • Blood Flow
  • Cardiovascular Physiological Phenomena
  • Cerebrovascular Disorders
  • Computers
  • Data Analysis
  • Flow
  • Heart Rate
  • Institutional Review Board
  • Measurement
  • Partial Pressure
  • Pressure Measurement
  • Statistical Analysis
  • Steady State

Readers

  • Combustion science or combustion engineering.
  • Materials Science
  • Radar Systems Engineering.