Extremity Regeneration of Soft Tissue Injury Using Growth Factor-Impregnated Gels

Abstract

All animal experiments have been completed. A second no cost extension has been approved in order to complete the remaining toxicology testing with CRO, Toxikon. These studies were delayed due to the COVID19 pandemic. All other experiments to evaluate the dose-response relationship, determine function of growth factor on nerve regeneration and function of each growth factor on independent nerve versus ischemic injuries have been completed. The Wyss Institute has completed work on the process and development of the alginate gels and growth factors.

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Document Details

Document Type
Technical Report
Publication Date
Oct 01, 2021
Accession Number
AD1156099

Entities

People

  • D.J. Mooney
  • E. J. Caterson
  • Ed Doherty
  • Leon Nesti
  • Sarah E. Kinsley
  • Simon G. Talbot

Organizations

  • Brigham and Women's Hospital

Tags

DTIC Thesaurus Topics

  • Arteries
  • Biomedical Research
  • Covid-19
  • Growth Factors
  • Health Services
  • Hospitals
  • Maryland
  • Materials
  • Medical Personnel
  • Models
  • Nerves
  • Personnel Management
  • Pharmacology
  • Soft Tissues
  • Tissues
  • United States
  • Wounds And Injuries

Readers

  • Clinical Trial Research.
  • Neuroscience
  • Polymer Science and Engineering.