Damaged Progenitors as Targets for Breast Cancer Prevention
Abstract
Moving new breast cancer prevention approaches forward into clinical trials requires robust data supporting both mechanism and efficacy. Our Breakthrough-funded study identified early changes in the breast cancer cell-of-origin. Here, we seek to understand these changes and the unique cell sensitivities they create, as a means of revealing new and unanticipated targets for breast cancer prevention. Our objectives are to unravel the mechanisms that give rise to the damaged cells and to reveal specific methods for eliminating them, thereby laying the groundwork for clinical trials of novel breast cancer prevention approaches.
Document Details
- Document Type
- Technical Report
- Publication Date
- Oct 01, 2021
- Accession Number
- AD1156247
Entities
People
- Leif W Ellisen