Impact of Operational Sleep Disruption on PTSD-Relevant Fear Learning Processes

Abstract

This report covers Year 3 of the project. This project examines the impact of disturbances in normal sleep and circadian regulation on mechanisms underlying vulnerability to, and maintenance of, posttraumatic stress disorder (PTSD). The goal of Year 3 was data collection and initial validation of data collection procedures and harmonization with Monash. We proposed to complete 15 participants (60 in total with year 1 and 2). Progress was slowed due to COVID19, which prompted our VA facility to shut down all human research the fall. Our study, which requires a hospital stay, was approved for collection in October with mitigation procedures in place limiting us to 1 subject/week. We have completed 18 subjects (% of target).

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Document Details

Document Type
Technical Report
Publication Date
Oct 01, 2021
Accession Number
AD1158223

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  • Victoria B Risbrough

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  • Biomedical

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  • Biomedical Research
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Readers

  • Circadian Sleep-Wake Regulation and Chronobiology
  • Clinical Trial Research.
  • Mental Health of Military Veterans with Posttraumatic Stress Disorder (PTSD): Risk Factors, Prevalence, Symptoms, and Treatment.