Understanding the Role of Gene-Environment Interactions in the Degeneration of Human Dopaminergic Neurons in Parkinson's Disease

Abstract

Gene environment interactions (GxE) are key to better understanding PD. We are testing pesticides for their effects in the dish, and in the context of mutations in the synuclein and GBA genes that are also being analyzed in Dr Ritzs epidemiologic cohort.

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Document Details

Document Type
Technical Report
Publication Date
Oct 01, 2021
Accession Number
AD1158227

Entities

People

  • Lee Rubin

Organizations

  • Harvard College

Tags

Communities of Interest

  • Biomedical
  • Engineered Resilient Systems

DTIC Thesaurus Topics

  • Biomedical Research
  • Cell Line
  • Cell Physiological Processes
  • Cells
  • Data Analysis
  • Data Mining
  • Diseases And Disorders
  • Genes
  • Genetics
  • Health Services
  • Information Science
  • Medical Personnel
  • Neurodegeneration
  • Neurons
  • Parkinson'S Disease
  • Proteins
  • Stem Cells

Fields of Study

  • Biology

Readers

  • Molecular and Cellular Biology
  • Neurodegenerative Parkinson's Disease and Rickettsial Disease handbook, including the data level of dopamine, BC, neurons, and PD.