A Case of Trimethoprim-Sulfamethoxazole Induced Aseptic Meningitis Masquerading as Septic Shock

Abstract

Trimethoprim-sulfamethoxazole induced aseptic meningitis(TSIAM) is a rare adverse drug reaction whose immunological basis is unknown, but based on symptoms is unlikely to be IgE mediated. It typically presents with fever, headache, neck pain, and/or altered mental status; the presence and severity of concomitant symptoms can vary. We describe a case of severe TSIAM which occurred after oral challenge to a single dose of trimethoprim-sulfamethoxazole (TS) and initially presented similarly to septic shock.

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Document Details

Document Type
Technical Report
Publication Date
Mar 15, 2022
Accession Number
AD1163536

Entities

People

  • Christopher Coop
  • Robert M Brooks

Organizations

  • 59th Medical Wing

Tags

DTIC Thesaurus Topics

  • Air Force
  • Body Regions
  • Central Nervous System
  • Department Of Defense
  • Emergency Medicine
  • Health Services
  • Hemorrhagic Shock
  • Infection
  • Literature Surveys
  • Meningitis
  • Nervous System
  • Pain
  • Side Effects
  • Skin Diseases
  • Stem Cells
  • Transplants
  • Viral Meningitis

Fields of Study

  • Medicine

Readers

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  • Immunology