Transcription Factor Analysis of SLE
Abstract
Purpose: Define transcription factors critical for SLE pathogenesis Scope:1) Expand chromatin marks to identify latent enhancers and regulatory regions relevant for SLE 2) Inhibit identified TF to define cellular effects. A key aspect was comparing different clinical subsets of SLE and using patients with rheumatoid arthritis as inflammatory controls. Major findings: Due to the pandemic, we only began our wet bench library preparation in January. We also suffered form the same pipeline supply chain issues as most molecular biology labs. Although we have data, we have not done any analysis.
Document Details
- Document Type
- Technical Report
- Publication Date
- Oct 01, 2021
- Accession Number
- AD1165682
Entities
People
- Kathleen E. Sullivan
Organizations
- Johns Hopkins School of Medicine