Multicenter Implementation Trial of Targeted Normoxia Strategy to Define Oxygen Requirements for Major Burn Patients: An Approach to Reduce Warfighter Morbidity, Deployed Logistical Burden of Oxygen, and Readiness Costs
Abstract
Oxygen therapy has undisputed importance in combat casualty care to treat/prevent morbidity associated with hypoxia. However, generous supplemental oxygen is routine, and often results in hyperoxia. Emerging evidence indicates that even modest hyperoxia can increases morbidity/mortality, however limited evidence exists specifically for trauma and burn patients. In addition, oxygen is a limited resource that is challenging to obtain in austere settingseg, prolonged field care and en route care, requiring substantial resources, space, weight, and logistics to procure. Therefore, it is critical to determine oxygen titration goals for combat injured to optimize care by reducing harm associated with hypoxia and hyperoxia and to conserve limited oxygen supply.
Document Details
- Document Type
- Technical Report
- Publication Date
- Jan 28, 2022
- Accession Number
- AD1167700
Entities
People
- Adit Ginde
Organizations
- University of Colorado Boulder