Reengineering of Antibiotics Informed by Antimicrobial Resistance Mechanisms

Abstract

Report on progress of using cryo-electron microscopy as a tool to understand the key interactions that the oxazolidinone antibiotic family make with the bacterial ribosome a swell as the means that the bacterial use to evolve resistance to this class of drugs.

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Document Details

Document Type
Technical Report
Publication Date
Jul 01, 2021
Accession Number
AD1172658

Entities

People

  • Matthew Belousoff

Organizations

  • Monash University

Tags

Communities of Interest

  • Biomedical

DTIC Thesaurus Topics

  • Anti-Bacterial Agents
  • Anti-Infective Agents
  • Bacteria
  • Bacterial Infections
  • Chemical Synthesis
  • Chemistry
  • Crystal Structure
  • Crystals
  • Electron Microscopy
  • Health Services
  • Infection
  • Microbiology
  • Microscopy
  • Molecular Dynamics
  • Organic Chemistry
  • Pharmacology
  • Proteins

Fields of Study

  • Biology

Readers

  • Educational Psychology
  • Microbial Pathology
  • Molecular Genetics

Technology Areas

  • Microelectronics