Intrawound Vancomycin Achieves Sustained High Interstitial Concentrations in Injured Human Extremities

Abstract

Intrawound vancomycin powder may prevent biofilm formation and reduce surgical site infections. Systemic levels of vancomycin after intrawound application inhuman subjects has not been thoroughly studied. Local levels of intrawound vancomycin powder have not been characterized through direct measurement techniques.

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Document Details

Document Type
Technical Report
Publication Date
Jul 31, 2022
Accession Number
AD1174185

Entities

People

  • Gerardo R. Garcia
  • Joseph C Wenke
  • Kevin Skevin Akers
  • Lee C. Mangum
  • Matthew Burgess
  • Miles Fisher
  • Robert J Christy
  • Sarah N. Pierrie
  • Taylor J. Bates
  • Thomas Lynch

Organizations

  • San Antonio Military Medical Center
  • United States Army Institute of Surgical Research
  • University of Texas Medical Branch

Tags

Communities of Interest

  • Biomedical

DTIC Thesaurus Topics

  • Anti-Bacterial Agents
  • Bone Fractures
  • Catheters
  • Chromatography
  • Clinical Trials
  • Combat Injuries
  • Creatinine
  • Databases
  • Debridement
  • Department Of Defense
  • Dermatologic Agents
  • Dialysis
  • Diameters
  • Infection
  • Liquid Chromatography
  • Membranes
  • Military Medicine
  • Surgery
  • Wound Infections

Readers

  • Microbial Pathology
  • Psychometric Testing or Psychological Assessment.
  • Trauma or Military Medicine

Technology Areas

  • Biotechnology