Comparison of Next Generation Diagnostic Systems (NGDS) for the Detection of SARS-CoV-2
Abstract
Diagnostic testing for infectious diseases is essential for force health protection and mission readiness and is consequently a high priority for the United States Department of Defense. The World Health Organization declared Coronavirus Disease 2019 (COVID-19) a pandemic in March 2020. Early in the pandemic, testing procedures for COVID-19 relied heavily on the use of nasopharyngeal (NP) swabs and real-time polymerase chain reaction (RT-PCR) assays targeting SARS-CoV-2, the virus that causes COVID-19. In addition, there were supply chain disruptions coupled with increased demand that led to shortages of essential laboratory supplies like viral transport media (VTM). The overlap of clinical symptoms between COVID-19 and illness caused by other respiratory pathogens underscores the need for specific and accurate multi-target detection assays. Furthermore, the discomfort of procuring nasopharyngeal swabs highlights the necessity to expand the types of biological specimens that can be used for diagnostic testing.
Document Details
- Document Type
- Technical Report
- Publication Date
- Jul 31, 2022
- Accession Number
- AD1174190
Entities
People
- Anna R. Ochoa
- Antonio O. Sanchez
- August Blackburn
- Chet R. Voelker
- Jennifer S. McDaniel
- Rachel E. Mahoney
- Sallie L. Hall
- Susana N. Asin
- Tony T. Yuan
Organizations
- United States Air Force