Bio-Integrated Sensor Patch Comprising Semiconducting Silicon Nanoneedles for Intratissue and Intracellular Recording
Abstract
The ability to efficiently record or transfer information from/to biological systems such as cells and tissues is limited by which current techniques suffer from the low temporal and spatial resolutions. This collaborative research aims to develop a mechanically flexible and elastic sensor patch that is capable of intimately interfacing with the curvilinear surface of biological systems in a minimally invasive manner. Uniquely, the sensor patch will include a vertically ordered array of semiconducting Si nanoneedles (Si NNs) to serve as the active sensing element that can measure high-level of electrophysiological signals at the nanoscale. The expected outcome will provide a first-of-its-kind mechanically compliant nanoprobe based on a vertically ordered array of Si NNs for efficient intracellular and intratissue recordings. The functionalities of the proposed nanoprobe platform can be potentially extendable to many other applications such as nanoscale electrical stimulations, on-demand localized drug deliveries, and optogenetic light-emitting diodes by modulating the embedded electronic properties and/or compositions of the nanoneedles.
Document Details
- Document Type
- Technical Report
- Publication Date
- Jun 02, 2022
- Accession Number
- AD1175111
Entities
People
- Chi Hwan Lee
Organizations
- Purdue University