Resuscitative Endovascular Balloon Occlusion of the Aorta (REBOA) at Altitude: Efficacy and Effects
Abstract
BACKGROUND: Non-compressible torso hemorrhage remains a leading cause of death. Resuscitative Endovascular Balloon Occlusion of the Aorta (REBOA) placement may occur prior to transport; however, its efficacy has not been demonstrated at altitude. We evaluated REBOA and Partial REBOA (pREBOA) utilization. We hypothesized that changes in altitude would not result in blood pressure changes proximal to a deployed REBOA. We also that the pREBOA balloon would function similarly to the ER-REBOA and therefore would be safe at altitude. CONCLUSION: ER-REBOA and p-REBOA catheters-maintained MAP up to 22,000 feet ft in an inanimate model. In the porcine model, ER-REBOA deployment improved MAP and the balloon remained effective at altitude. The pREBOA results suggest that the pREBOA balloon is efficacious at altitude and reduces the ischemia-reperfusion injury while maintaining lower extremity perfusion compared to a fully occlusive aortic balloon. In addition, partial aortic occlusion allowed for the mitigation of the additional insult of altitude that would otherwise exacerbate the ischemia/reperfusion inherent to aortic occlusion for hemorrhage control.
Document Details
- Document Type
- Technical Report
- Publication Date
- Mar 21, 2022
- Accession Number
- AD1176446
Entities
People
- Amy T. Makley
- Gerald Fortuna
- Jackie Youngs
- Joseph J. Dubose
- Kathleen E. Singer
- Mackenzie C. Morris
- Mary F. Stuever
- Michael D Goodman
- Rebecca Schuster
- Rosalie Veile
- Sabre M. Stevens-topie
- Taylor E. Wallen
- Thomas C Blakeman
Organizations
- United States Air Force School of Aerospace Medicine
- University of Cincinnati