Incidence of Mild Cognitive Impairment in Gulf War Veterans

Abstract

The goal of this project is to evaluate whether Gulf War Veterans are developing Mild Cognitive Impairment (MCI)earlier, and at a higher than expect rate. On the continuum of cognitive decline, mild cognitive impairment (MCI) is considered the transition between cognitive impairment associated with normal aging and the more serious decline associated with dementia. The projects specific aims are to cross-validate preliminary findings of a higher than expected rate of MCI, hippocampal atrophy, and parietal cortex thinning in the Gulf War Illness Consortium(GWIC) cohort; (2) to examine global white matter hyperintensities (WMH) volume from the MRIs of GW veterans with and without MCI from the San Francisco Veterans Administration and GWIC cohorts; and (3) to investigate whether GW veterans with MCI fit the National Institute on Aging and Alzheimers Association (NIA-AA) research framework characterization of Alzheimer's disease (AD) by examining levels of A-beta.

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Document Details

Document Type
Technical Report
Publication Date
Aug 01, 2022
Accession Number
AD1180342

Entities

People

  • Linda L Chao

Organizations

  • Northern California Institute for Research and Education

Tags

DTIC Thesaurus Topics

  • Abstracts
  • Alzheimer Disease
  • Biomedical Research
  • Brain Injuries
  • Cellular Structures
  • Cognitive Impairment
  • Consortiums
  • Dementia
  • Department Of Defense
  • Diseases And Disorders
  • Education
  • Medical Personnel
  • Neurodegeneration
  • Neuroimaging
  • Parkinson'S Disease
  • Persian Gulf Syndrome
  • Professional Development
  • Standards
  • Students
  • Training

Fields of Study

  • Psychology

Readers

  • Auditory Neuroscience/Auditory Physiology.
  • Gulf War Illness and Chronic Multisymptom Illness in Veterans.
  • Neuroscience