Comparison of Preoperative Methylprednisolone and Ibuprofen on Mandibular Anesthesia Efficacy

Abstract

Pain management is a critical component for a successful appointment during endodontic procedures. The most common method for delivering mandibular pulpal anesthesia is an inferior alveolar nerve block (IANB). Success rates for achieving adequate pulpal anesthesia range from 25% to 90%. A prominent theory for anesthetic failure is the presence of pulpal inflammation. Symptomatic irreversible pulpitis activates the inflammatory response and increases the production of pain producing neuropeptides and anesthetic resistant sodium channels. Recent clinical trials and systematic reviews have shown an increase in successful anesthesia using a preoperative nonsteroidal anti-inflammatory drug (NSAID). Furthermore, a clinical trial found a greater increase in IANB efficacy using a low dose corticosteroid in comparison to an NSAID in asymptomatic patients.

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Document Details

Document Type
Technical Report
Publication Date
Jun 01, 2020
Accession Number
AD1182804

Entities

People

  • Russell L Neal

Organizations

  • Uniformed Services University of the Health Sciences

Tags

DTIC Thesaurus Topics

  • Anatomy
  • Anesthesia
  • Anesthetics
  • Anti-Inflammatory Agents
  • Clinical Trials
  • Dentistry
  • Drug Therapy
  • Endocrine Glands
  • Health Services
  • Local Anesthetics
  • Oral Surgery
  • Pain
  • Pain Management
  • Peptides
  • Root Canal
  • Sequential Analysis
  • Teeth
  • Test And Evaluation
  • Therapy

Fields of Study

  • Medicine

Readers

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