Preventative Strategies for Dental Caries using Phage Therapy

Abstract

The treatment of dental caries is progressing towards preventative measures. Current modalities include patient education and the use of fluoridated communal water supplies. A new preventative strategy is being researched to treat a different aspect of caries prevention- targeted viral therapy. Infection of Streptococcus mutans with bacteriophages, which causes bacteria to lyse and thereby halts the caries progression, is being researched. The purpose of this study was to discover naturally occurring bacteriophages that target S. mutans, the bacteria responsible for the initiation of caries.

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Document Details

Document Type
Technical Report
Publication Date
May 14, 2021
Accession Number
AD1182964

Entities

People

  • Sharon L Aradine

Organizations

  • Uniformed Services University of the Health Sciences

Tags

DTIC Thesaurus Topics

  • Anti-Bacterial Agents
  • Anti-Infective Agents
  • Army Personnel
  • Bacteria
  • Bacteriophages
  • Biology
  • Biomedical Research
  • Cell Physiological Processes
  • Craniocerebral Trauma
  • Department Of Defense
  • Diseases And Disorders
  • Education
  • Identification Systems
  • Medical Personnel
  • Microbiology
  • Microbiomes
  • Research Facilities
  • Streptococcus
  • Streptococcus Phages
  • Teeth
  • Tooth Diseases
  • Universities
  • Wounds And Injuries

Fields of Study

  • Medicine

Readers

  • Chemistry (specifically Chemical Fluorescence)
  • Educational Psychology
  • Oncology (Cancer Research).