Comparison of Preoperative Methylprednisolone and Ibuprofen on Mandibular Anesthesia Efficacy
Abstract
Effective pain control is vital to the practice of modern dentistry. Mandibular pulpal anesthesia is commonly achieved using an inferior alveolar nerve block (IANB). Irreversible pulpitis however, can reduce IANB success to as low as 20%. This high failure rate has been attributed to the inflammatory process. Both nonsteroidal anti-inflammatory medications (NSAIDs), and corticosteroid medications have been reported to increase IANB success in inflamed tissues. One clinical trial demonstrated the superiority of a steroid medication over NSAIDs in non-inflamed tissues. To date, no study has compared these two medications in inflamed pulp tissue. This prospective, double-blind, randomized clinical trial will compare IANB success inpatients with symptomatic irreversible pulpitis when given ibuprofen or methylprednisolone prior to initiating endodontic treatment.
Document Details
- Document Type
- Technical Report
- Publication Date
- Jun 01, 2021
- Accession Number
- AD1182982
Entities
People
- Jeffrey M. Clark
Organizations
- Uniformed Services University of the Health Sciences