The Effect of Liposomal Bupivicaine on Opioid Prescription Refills after Third Molar Surgery at Carl R. Darnall Medical Center (CRDAMC)
Abstract
Purpose: The purpose of this Pilot Observational Retrospective Study was to assess if the use of Liposomal Bupivacaine (LB) as an adjunctive anesthetic to the surgical protocol in the extraction of partially bony and full bony impacted third molar teeth at Carl R. Darnall Army Medical Center (CRDAMC) Oral Maxillofacial Surgery (OMFS) Department significantly reduced the total Morphine Milligram Equivalent (MME) amount prescribed when compared to a surgical protocol that did not utilize LB as an adjunct. Methods: An Observational Retrospective Cohort Longitudinal study was conducted via three collection methods: an archival dental chart review executed by the principle investigator; a collated opioid report provided by the Pharmacy DATA Transaction Service, and finally, the Surgeons Log for services provided at CRDAMC. Data analysis was developed using a two-tailed T- Test and an established P value of 0.05.Results: The statistical analysis demonstrated no significant difference in regards to the total MME prescribed when LB was routinely used as a surgical anesthetic adjunct in the extraction of partial/full bony third molar impacted teeth from 01 August 2020 to 31 August 2021, when compared to the time frame 01 July 2019 to 31 July 2020, when LB was not used as a surgical anesthetic adjunct. There was no significant difference in the number of pills dispensed in relation to the number of extracted teeth, nor the MME to the severity of the impacted teeth that were extracted. Conclusion: In this study, the introduction of LB has not yet led to a decrease in post-operative opioid prescribing by the OMFS clinic at CRDAMC. More research is necessary to evaluate the effectiveness of LB as an adjunct for post-operative pain after third molar extraction. A randomized clinical trial that monitors real-time opioid prescribing and consumption would likely provide clinically relevant data.
Document Details
- Document Type
- Technical Report
- Publication Date
- Mar 21, 2022
- Accession Number
- AD1186294
Entities
People
- David R. Maxwell
Organizations
- Uniformed Services University of the Health Sciences