Analytic-Directed Multi-scale Synthesis System
Abstract
Major Goals: a. Background: The initial schedule of tasks and milestones as contracted organized the project into three phases, with each phase having two subdivisions (A and B). Phase 1A was completed at month 9, phase 1B at month 18; phase 2A at month 26, phase 2B at month 34, phase 3A at month 41 and phase 3B at month 48. At the end of Phase 1A, following guidance provided by DARPA at the review meeting of August 2016, as well as subsequent internal brainstorming sessions, and interactions with the DARPA program management and with our outside Advisory Committee, a revised list of tasks and milestones was approved. This updated plan reorganized our tasks and milestones to shift effort from the analytic-directed multi-scale synthesis system to a rapid automated reaction screening system, including a commercialization effort. At the end of phase 3B, a 9-month NCE was granted based on the remaining tasks and milestones described below and a second 6-month NCE was granted due to the disruption of experiments caused by the Covid pandemic. Below, due to text limitations, we report the completion % for the tasks and milestones along with a short update on progress over the last project year. Two new tasks, namely enzymatic bioassays and small-scale synthesis and product collection, were added as informal parts of the NCE.
Document Details
- Document Type
- Technical Report
- Publication Date
- May 17, 2021
- Accession Number
- AD1186594
Entities
People
- R. G. Cooks
Organizations
- Purdue University