Wireless, Bioresorbable Neural Stimulators for Discovery in Neuroscience
Abstract
Major Goals: Background: Bioresorbable electronic systems represent an emerging class of technology that will create important, new categories of devices with powerful modes of use in emergency medicine, recovery and rehabilitation - each of critical relevance to the care of wounded armed services personnel. Systems with demonstrated utility in animal models include (1) 'electroceuticals' for eliminating surgical site infections, (2) temporary pacemakers for enhancing recovery cardiac surgery, (3) nerve and bone growth stimulators for accelerated healing and (4) intracranial sensors for monitoring patients with traumatic brain injury. In these and other cases, the devices provide high performance, stable operation for a clinically relevant timeframe, and then completely resorb to eliminate unnecessary device load on the body. The major goal is to establish the broad scientific foundations for this emerging technology. Two test bed applications - one in accelerated neuroregeneration and another in enhanced recovery from traumatic brain injuries - will serve to orient and focus the basic research efforts around specific requirements. The work is organized into three parts: (1) Materials Science for High Performance Devices (2) Scaled Processes for Processing, Assembly and Integration and (3) Applications in Emergency Care and Rehabilitation. Successful outcomes from this research have the strong potential to lead to profound improvements in costs and outcomes in military health care.
Document Details
- Document Type
- Technical Report
- Publication Date
- Mar 31, 2021
- Accession Number
- AD1187579
Entities
People
- John A. Rogers
Organizations
- Northwestern University