Toxicology Assessment for Safer Alternatives For Readiness (SAFR) Securing the Availability of Green, Enhanced Coatings (SAGE) 20-04 - Infrared Colorful and Responsive Green Coating - Xanthommatin

Abstract

Xanthommatin (Xa) is a natural pigment found in insect and crustacean exoskeletons that is proposed as a colorant for paints and coatings of military interest. The Army Public Health Center evaluated the toxicity of Xa using in silico and in vitro approaches, as well as a literature review and toxicity assessment of Xa to identify environmental and human health hazards. The Xa is not predicted to be an environmental or ecological hazard. The Xa was negative in the Ames assay for bacterial mutagenicity. Based on in vitro testing and in silico modeling, Xa is predicted to be a skin sensitizer; however, the potency of Xa was not characterized. It is recommended that additional skin sensitization testing be conducted to reduce uncertainty of this occupational hazard.

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Document Details

Document Type
Technical Report
Publication Date
Oct 30, 2022
Accession Number
AD1187656

Entities

People

  • Jorge Ruiz
  • Valerie H. Adams

Organizations

  • United States Army Center for Health Promotion and Preventive Medicine

Tags

DTIC Thesaurus Topics

  • Abstracts
  • Animals
  • Cells
  • Chemical Properties
  • Chemical Synthesis
  • Chemistry
  • Colorants
  • Department Of Defense
  • Environment
  • Environmental Protection
  • Health
  • Hygiene
  • Occupational Safety And Health
  • Public Health
  • Test And Evaluation
  • Toxicity
  • Toxicology

Readers

  • Aviation Safety Risk Assessment.
  • Geochemistry
  • Toxicology/Environmental Toxicology