Characterizing Hyperoxia-Induced Alterations in Muscular Physiology: Part 1
Abstract
Mechanisms underlying decreased aerobic performance after long duration 100% oxygen (O2) dives are unknown. 10 subjects completed 6-hour dry dives on 3 consecutive days while breathing 100% O2 at 1.35 ATA. Aerobic performance with metabolic and respiratory parameters were completed before diving, post-dive 3, and 48 hr. after dive 3. Blood oxidative stress samples were collected on dive days before diving, at 3 and 6 hr. during the dive, 30 and 60 min post-dive, and 16 and 48 hr after dive 3. Nerve conduction velocity (NCV) was performed before and after each dive. Aerobic performance decreased (p = .021) after dive 3 compared to baseline (6.4 +/- 1.8 min vs. 5.3 +/- 2.0 min, p = .037), but not at 48-hr post-dive 3. VO2 (p = .001) and heart rate (HR) (p = .013) decreased during aerobic performance at post-dive 3 (VO2: p = .009, HR: p =.010) compared to baseline. VO2 (p = .005) remained lower at 48-hr post-dive 3. No other metabolic or respiratory parameters changed. Systemic oxidative stress makers and NCV were unaffected. Aerobic performance is reduced after 6-hour 100% O2 dives on 3 consecutive days. Unfortunately, the measured variables do not fully explain performance decrements.
Document Details
- Document Type
- Technical Report
- Publication Date
- Jun 01, 2022
- Accession Number
- AD1188634
Entities
People
- Alex O. Klemp
- Elizabeth G. Considine
- Mitchell D. Reed
Organizations
- United States Navy Experimental Diving Unit