Development of Objective Electrophysiological Tests for Tinnitus Based on Long-Lasting After-Discharges in the Inferior Colliculus

Abstract

Tinnitus is the sensation of ringing in the ears in the absence of a corresponding, physical sound and is a symptom of a pathological response of the auditory system. It is common in the aging population and in military veterans in particular. Most often, tinnitus is associated with hearing loss due to exposure to loud noise. There is no objective or diagnostic test for tinnitus, little understanding of its causes, and no curative treatment. This projects goal is to create an electrophysiological test for tinnitus. We have shown that there are measurable and detectable changes in the electrophysiological activity in the central auditory system in response to a long-duration sound; this is a long-lasting after discharge where neurons continue to fire 2-3minutes after the sound has stopped.

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Document Details

Document Type
Technical Report
Publication Date
May 01, 2022
Accession Number
AD1190415

Entities

People

  • Douglas L. Oliver

Organizations

  • University of Connecticut Health Center

Tags

DTIC Thesaurus Topics

  • Abstracts
  • Animals
  • Biomedical Research
  • Brain
  • Connecticut
  • Correlation Analysis
  • Electrophysiological Phenomena
  • Electrophysiology
  • Frequency
  • Hearing Disorders
  • Hearing Loss
  • Institutional Review Board
  • Laboratory Animals
  • Maryland
  • Medical Personnel
  • Military Personnel
  • Neurosciences
  • Otorhinolaryngology
  • Patent Applications
  • Professional Development
  • Standards
  • Students
  • Tinnitus

Fields of Study

  • Medicine

Readers

  • Auditory Neuroscience/Auditory Physiology.