Developing Personalized Medicine Strategies to Increase Physical Activity in Parkinson's Disease (PD) Through Digital Health Technology

Abstract

Increasing physical activity levels in people with Parkinson's disease (PD) is a major unmet need. Objectives are to investigate whether: 1) Protocols using gamification to increase physical activity in patients with PD employing remote intervention and assessment will be feasible and acceptable to participants; 2) Individual NMS will predict responsiveness to a gamification intervention targeting physical activity levels facilitating a personalized approach in future efficacy studies; 3) Changes in physical activity will be associated with changes in motor symptoms, measured using the wearable Parkinson's Kinetograph (PKG). This is a prospective observational study. Using administrative databases and review of medical records, we will identify and remotely enroll 85 Veterans with PD on stable medication regimens into a protocol. Personalized strategies using digital health technology to increase physical activity will be highly scalable, improving the symptoms and lives of countless people living with PD.

Open PDF

Document Details

Document Type
Technical Report
Publication Date
Oct 01, 2022
Accession Number
AD1190862

Entities

People

  • James Morley
  • Kimberly Waddell

Tags

DTIC Thesaurus Topics

  • Agent Orange
  • Biomedical Research
  • Biomedical Technology
  • Clinical Trials
  • Communication Disorders
  • Data Analysis
  • Department Of Defense
  • Diseases
  • Education
  • Gamification
  • Health
  • Medical Personnel
  • Monitoring
  • Movement Disorders
  • Parkinson'S Disease
  • Personalized Medicine
  • Physical Activity
  • Professional Development
  • Students
  • Training

Fields of Study

  • Medicine
  • Psychology

Readers

  • Enterprise Information Systems Architecture and Joint Command Capability Interoperability Support.
  • Neurodegenerative Parkinson's Disease and Rickettsial Disease handbook, including the data level of dopamine, BC, neurons, and PD.
  • Neurotrauma and Rehabilitation Medicine.