Strain-Programmable Bioadhesive Patch for Accelerated Healing of Diabetic Ulcer

Abstract

We have accomplished all tasks that were proposed for months 1-12. More specifically, in collaboration with Veves team, my team designed and validated the strain-programmable patch(Subtask 1), carried out theoretical analysis and experimental validation the patch (Subtask2), and characterized the patch (Subtask 3). Furthermore, we assisted Veves team to complete all proposed animal studies that evaluated the in vivo biocompatibility of the patch (Subtask4). Our collaborative results were very positive and resulted in a publication in a journal of major impact (Theocharidis et all. Strain-Programmed Patch for Diabetic Wound Healing.Nature Biomedical Engineering, https://doi.org/10.1038/s41551-022-00905-2). We also achieved all proposed milestones.

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Document Details

Document Type
Technical Report
Publication Date
Jul 01, 2022
Accession Number
AD1190888

Entities

People

  • Xuanhe Zhao

Organizations

  • Massachusetts Institute of Technology

Tags

DTIC Thesaurus Topics

  • Adhesives
  • Biomedical Engineering
  • Biomedical Research
  • Department Of Defense
  • Engineering
  • Fabrication
  • Feedback
  • Foot Diseases
  • Information Operations
  • Law
  • Maryland
  • Massachusetts
  • Materials
  • Mechanical Properties
  • Medical Personnel
  • Optimization
  • Patent Applications
  • Professional Development
  • Shear Strength
  • Skin Grafts
  • Students
  • Technology Transfer
  • Tissue Adhesives
  • Validation
  • Wound Healing

Readers

  • Technical Research and Report Writing.
  • Trauma Surgery or Emergency Medicine.

Technology Areas

  • Biotechnology