Increasing HPV Vaccination Coverage Among Adolescent and Young Adult (AYA) Cancer Survivors: A Multilevel Intervention
Abstract
Survivors of childhood cancer are 2.8 times more likely to develop a secondary human papillomavirus (HPV)-associated cancer than the general population. Unfortunately, HPV vaccination coverage among survivors of childhood cancer is even lower than that in the general population. Further, due to concerns about reduced immunogenicity in the setting of previous immunosuppressive cancer therapy, 3 doses of the HPV vaccine are recommended for all survivors of childhood cancer regardless of age at initiation of vaccination. The purpose of this study is to increase HPV vaccination initiation and 3-dose completion among survivors of childhood cancer, defined as age 25 years of age or younger at cancer diagnosis. This study employs a multilevel approach, including a quality improvement intervention targeting the oncologists and clinic staff to routinely provide a strong recommendation for HPV vaccination. The study will also test the efficacy of a game-based learning avatar-navigated mobile (GLAm) app versus usual care at the patient/caregiver level to increase vaccination initiation and completion independent of the clinic visit in a randomized controlled clinical trial.
Document Details
- Document Type
- Technical Report
- Publication Date
- Sep 01, 2022
- Accession Number
- AD1191014
Entities
People
- Deanna Teoh
Organizations
- University of Minnesota