Boston Biorepository, Recruitment, and Integrative Network (BBRAIN) for GWI

Abstract

The primary objective of BBRAIN is to establish a retrospective and prospective biorepository network for GWI research by data mining from existing BBRAIN collaborator specimens and for recruiting 500 additional repository samples. The four prospective recruitment resource sites include Boston, Miami, Bronx and San Francisco. The BBRAIN structure provides centralized cataloguing and coordination of retrospective biorepository samples from 10 collaborating institutions who are sharing existing blood plasma, sera, PBMCs, cerebrospinal fluid, human induced pluripotent stem cells (hiPSCs), DNA and saliva samples. Corresponding cognitive outcomes, brain imaging, demographics and health symptom surveys are included in the BBRAIN network datasets to allow for the comparison of biomarkers with behavioral outcomes.To date, data usage and material transfer agreements have been put in place with all sites and sharing has begun with retrospective data and outcomes.

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Document Details

Document Type
Technical Report
Publication Date
Sep 01, 2022
Accession Number
AD1191035

Entities

People

  • Kimberly Sullivan

Organizations

  • Boston University Medical Campus

Tags

Communities of Interest

  • Autonomy
  • C4I
  • Engineered Resilient Systems
  • Ground and Sea Platforms
  • Weapons Technologies

DTIC Thesaurus Topics

  • Brain
  • Brain Injuries
  • Cells
  • Chemical Synthesis
  • Chemistry
  • Computational Science
  • Data Mining
  • Demography
  • Health Services
  • Information Processing
  • Information Science
  • Medical Personnel
  • Network Science
  • Neurodegeneration
  • Stem Cells

Readers

  • Clinical Trial Research.
  • Psychological Intervention/Treatment for Stress, Anxiety, PTSD, and Related Emotional and Cognitive Health Symptoms.

Technology Areas

  • AI & ML
  • Biotechnology