Composition, Function, and Role of the Intestinal Microbiome in Pediatric Heart Failure and Heart Transplantation

Abstract

The role of the intestinal microbiome has gained substantial interest as a novel marker for prognosis of disease and as a potential target for therapeutic intervention. There is evidence that the microbiome exerts a fundamental influence on immunity, can be altered in heart failure,and can be further disrupted by immunosuppressive medications. This indicates the potential significant impact that alterations to the intestinal microbiome may play in the care of children who have undergone heart transplant.

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Document Details

Document Type
Technical Report
Publication Date
Jun 01, 2022
Accession Number
AD1191147

Entities

People

  • Joseph Spinner

Organizations

  • Baylor College of Medicine

Tags

DTIC Thesaurus Topics

  • Abstracts
  • Adaptive Immunity
  • Bacteroidaceae
  • Bacteroidetes
  • Biomedical Research
  • Covid-19
  • Data Analysis
  • Diseases
  • Extraction
  • Health Services
  • Heart Diseases
  • Heart Failure
  • Liquid Chromatography
  • Medical Personnel
  • Microbiomes
  • Professional Development
  • Research Facilities
  • Social Distancing
  • Transplants

Fields of Study

  • Biology
  • Medicine

Readers

  • Immunology
  • Neuroscience
  • Psychological Intervention/Treatment for Stress, Anxiety, PTSD, and Related Emotional and Cognitive Health Symptoms.

Technology Areas

  • Biotechnology