Minimally Invasive VAC Therapy with Instillation for Treating Infected Skin-Implant Interfaces in Percutaneous Osseointegrated Devices

Abstract

Percutaneous osseointegrated (OI) prosthetics are a superior alternative to socket-type prosthetics. Sadly, the weak link of this OI technology is high and re-occurring infections that originate from the implant post-exit sites. One potential method for treating infected tissue locally is the direct application of negative pressure wound therapy with instillation (NPWTi) at the implant exit site. Thus, this proposal's overall goal is to successfully develop an NPWTi treatment plan for infected skin-implant interfaces of percutaneous OI devices. We have designed, developed, and fabricated all necessary implants and tools during this reporting period and obtained the required institutional approvals. We have now performed initial surgery on a group of 20 rats. They are currently being inoculated with bacterial for starting the NPWTi treatments.

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Document Details

Document Type
Technical Report
Publication Date
Aug 01, 2022
Accession Number
AD1191228

Entities

People

  • Jay Agarwal
  • Sujee Jeyapalina

Organizations

  • University of Utah

Tags

DTIC Thesaurus Topics

  • Abstracts
  • Anti-Bacterial Agents
  • Anti-Infective Agents
  • Bacteria
  • Biomedical Research
  • Bone Diseases
  • Contracts
  • Department Of Veterans Affairs
  • Health Care
  • Health Services
  • Infection
  • Medical Personnel
  • Prosthetics
  • Rodents
  • Skull
  • Standards
  • Staphylococcus Aureus
  • Students
  • Therapy
  • Tissues
  • Universities

Readers

  • Systems Analysis and Design
  • Trauma Surgery or Emergency Medicine.