Dosing of Overground Robotic Gait Training with Functional Outcomes and Neuroplasticity After Spinal Cord Injury (DOOR SCI)
Abstract
The goals of this project are 1) to conduct a randomized controlled trial to prospectively examine whether the dosing frequency [24 sessions delivered as high, moderate, or low frequency, defined by number days/week (4, 3, or 2 days/week over 6, 8, 12 weeks)] of robotic gait training (RGT) therapy provided during the acute/subacute recovery phase after incomplete SCI impacts outcomes compared to usual care only; 2)investigate the difference over 9 months of the neuroplastic effect of RGT dosing as measured by single pulse TMS; and 3) evaluate the safety, tolerability, and feasibility of delivering different dosing frequency levels of RGT from inpatient to outpatient rehabilitation settings. Over year 1 of the project, we achieved all IRB and HRPO approvals, initiated our advisory board and DSMB meetings, completed study team trainings and began participant recruitment and data collection. By grant year 1 end, we had enrolled 7 participants.
Document Details
- Document Type
- Technical Report
- Publication Date
- Oct 01, 2022
- Accession Number
- AD1192027
Entities
People
- Chad Swank
- Christa Ochoa
- Faith Meza