The Effects of Vibration on Indicators of Post-Traumatic Knee Osteoarthritis Risk Following Anterior Cruciate Ligament Injury

Abstract

The purpose of this study is to determine the effects of whole body vibration (WBV) and local muscle vibration (LMV) on quadriceps function, gait biomechanics, patient-reported outcomes, imaging markers of knee joint health, and the incidence of post-traumatic knee osteoarthritis in individuals with anterior cruciate ligament reconstruction (ACLR). Patients will be randomized to 1 of 3 study arms: standard rehabilitation, standard rehabilitation + WBV, or standard rehabilitation + LMV, and the study outcomes we be assessed prospectively over the first year following ACLR. Patients will be recruited from the UNC Orthopaedics and Womack Army Medical Center. We hypothesize that both forms of vibration will enhance quadriceps function and gait biomechanics more effectively than standard rehabilitation, thus resulting better patient-reported outcomes and knee joint health, and a lower risk of post-traumatic knee osteoarthritis. To date we have 1) hired and trained all study personnel, 2) received local IRB and HRPO approval, 3) engaged with Womack Army Medical Center to establish IRB rely-on approval, 4) procured vibration devices for the rehabilitation clinics, 5) developed a laboratory standard operating procedures manual, and 6) enrolled the first 9 patients.

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Document Details

Document Type
Technical Report
Publication Date
Oct 01, 2022
Accession Number
AD1192590

Entities

People

  • Jonathan T Blackburn

Organizations

  • University of North Carolina at Chapel Hill

Tags

DTIC Thesaurus Topics

  • Acquisition
  • Active Duty
  • Arthritis
  • Biomedical Research
  • Blood Coagulation
  • Clinical Trials
  • Data Processing
  • Department Of Defense
  • Electronic Mail
  • Internet
  • Jointsanatomy
  • Ligaments
  • Management Personnel
  • Medical Personnel
  • North Carolina
  • Orthopedics
  • Professional Development
  • Quality Control
  • Skin Diseases
  • Software Development
  • Standards
  • Students
  • Technology Transfer

Fields of Study

  • Medicine

Readers

  • Aviation Safety Risk Assessment.
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  • Rehabilitation and Prosthetic Care for Military Service Members and Veterans with Limb Loss or Disability.