Extracellular RNA: Novel Biomarker and Potential Therapeutic Target in Trauma
Abstract
Traumatic injury is a major cause of combat casualty and modality. Trauma can induce profound systemic inflammatory responses and multiple remote organ damage. While the clinical manifestations/courses of traumatic injury have been well described, the molecular mechanism leading to inflammation and organ failure is poorly understood. Moreover, rapid aeromedical evacuation has been used in battlefield to save lives, but also has subjected warfighters to hypobaric conditions. How hypobaric conditions impact the body's immune system and its response to traumatic injury is unclear.
Document Details
- Document Type
- Technical Report
- Publication Date
- May 20, 2022
- Accession Number
- AD1193820
Entities
People
- Wei Chao
Organizations
- University of Maryland