Standard Practice for Wildlife Toxicity Reference Values

Abstract

This Technical Guide (TG) provides guidance for developing Toxicity Reference Values (TRVs) that are used in performing Ecological Risk Assessments at military sites. A Wildlife Toxicity Assessment (WTA) documents derivation of individual TRVs for compounds of interest to the DoD. This revised TG was updated from a previous guidance document published in 2000 to include an expanded discussion on the process for performing a detailed literature review. TRV derivations using No Observed Adverse Effect Levels (NOAEL) and Lowest Observed Adverse Effect Level (LOAEL) are similar to the previously published guidance. An updated Benchmark Dose procedure includes discussion on using a Bayesian Benchmark Dose approach (BBMD).

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Document Details

Document Type
Technical Report
Publication Date
Feb 21, 2023
Accession Number
AD1193997

Entities

People

  • Glenn J. Leach
  • Mark A. Williams
  • Mark S. Johnson
  • Michael J. Quinn

Tags

DTIC Thesaurus Topics

  • Accuracy
  • Animals
  • Chemical Synthesis
  • Chemistry
  • Data Mining
  • Databases
  • Environmental Exposure
  • Environmental Health
  • Environmental Monitoring
  • Environmental Protection
  • Governments
  • Health
  • Information Science
  • Materials
  • Medical Personnel
  • Monte Carlo Method
  • Public Health
  • Risk
  • Risk Analysis
  • Risk Management
  • Rodents
  • Standards
  • Test And Evaluation
  • Toxicology
  • Wildlife

Readers

  • Computational Modeling and Simulation
  • Library and Information Science
  • Toxicology/Environmental Toxicology

Technology Areas

  • AI & ML
  • AI & ML - Bayesian Inference